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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GATA2 All Species: 19.7
Human Site: S227 Identified Species: 36.11
UniProt: P23769 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23769 NP_001139133.1 480 50500 S227 S M K M E S G S P L R P G L A
Chimpanzee Pan troglodytes XP_507651 444 47996 S201 M K L E S S H S R G S M T A L
Rhesus Macaque Macaca mulatta XP_001097801 480 50467 S227 S M K M E S G S P L R P G L A
Dog Lupus familis XP_541740 480 50435 S227 S M K M E S G S P L R P G L A
Cat Felis silvestris
Mouse Mus musculus O09100 480 50449 S227 S M K M E G G S P L R P G L A
Rat Rattus norvegicus Q924Y4 480 50445 S227 S M K M E G G S P L R P G L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506274 481 52429 L228 N Q V K L P E L L A S G R L F
Chicken Gallus gallus P23824 466 50132 A213 E G M K M E S A S P L R S S L
Frog Xenopus laevis P23770 452 48922 S205 G G S P L R S S L A P M G T Q
Zebra Danio Brachydanio rerio Q91428 438 47572 R195 K L D S A H S R S M A S I G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91623 486 50616 V205 G P S E Y Q A V M N A F M H Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P28515 416 44804 T173 T G L A G C S T S S G S S S A
Sea Urchin Strong. purpuratus NP_999704 431 45512 A188 M S E L P N S A L N F H H P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.9 99.7 98.9 N.A. 97.9 97.5 N.A. 46.5 87.2 83.9 63.3 N.A. 36.4 N.A. 28.9 40.8
Protein Similarity: 100 72 99.7 99.5 N.A. 98.5 98.5 N.A. 54.4 91.2 87.5 71.6 N.A. 48.3 N.A. 41.4 53.5
P-Site Identity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. 6.6 0 13.3 6.6 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. 13.3 6.6 13.3 20 N.A. 0 N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 8 16 0 16 16 0 0 8 54 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 8 16 39 8 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % F
% Gly: 16 24 0 0 8 16 39 0 0 8 8 8 47 8 8 % G
% His: 0 0 0 0 0 8 8 0 0 0 0 8 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 8 8 39 16 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 16 8 16 0 0 8 24 39 8 0 0 47 16 % L
% Met: 16 39 8 39 8 0 0 0 8 8 0 16 8 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 16 0 0 0 0 0 % N
% Pro: 0 8 0 8 8 8 0 0 39 8 8 39 0 8 0 % P
% Gln: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 16 % Q
% Arg: 0 0 0 0 0 8 0 8 8 0 39 8 8 0 0 % R
% Ser: 39 8 16 8 8 31 39 54 24 8 16 16 16 16 0 % S
% Thr: 8 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % T
% Val: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _